5 Stars
See prices from 10 sites
from$241
See prices from 10 sites
from$241
  • reception
  • bedroom

1 / 61

About 21c Museum Hotel Louisville

  • On-site Proof on Main Restaurant

    Dine at the acclaimed Proof on Main restaurant for farm-to-table cuisine and inventive local dishes.

  • 24/7 Contemporary Art Museum Access

    Explore the multi-venue contemporary art museum located directly within the hotel premises at any hour of the day.

  • Potential Guest Room Noise

    Guest rooms may experience noise transfer from adjacent rooms or hallway activity due to building construction.

  • High-End Guest Room Amenities

    Relax in rooms featuring 50-inch HDTVs, Lavazza coffee machines, and designer Malin+Goetz toiletries.

  • Full Service Fitness Center

    Maintain your wellness routine using the on-site fitness center equipped with a sauna, steam room, and massage treatment options.

  • Convenient Valet Parking Services

    Utilize the 24-hour valet parking service available directly at the hotel for seamless vehicle storage.

  • Central Downtown Louisville Location

    Walk to the Louisville Slugger Museum, Muhammad Ali Center, and various Whiskey Row distilleries from this historic West Main Street property.

  • Limited Natural Room Lighting

    Some guest accommodations feature minimal natural light despite the presence of windows.

The 5-star 21c Museum Hotel Louisville is set within five renovated 19th-century bourbon and tobacco warehouses, functioning as both a hotel and a contemporary art museum. It features the award-winning Proof on Main restaurant, serving American cuisine with a Southern twist, and displays a prominent golden David sculpture visible from a distance. Guests can experience the unique Asleep in the Cyclone room art installation or encounter the iconic red penguin art installations throughout the property. The hotel has a review score of 9.2 based on over 5,000 reviews, with atmosphere, restaurant, and overall experience highlighted positively by guests.

This summary was created by AI and might not be 100% accurate.

Rooms

  • Deluxe Double Room, 2 Double Beds

    • 1 2 Double Beds
    • Sleeps 4
    • 335 sq ft
  • Luxury Double Room, 2 Double Beds

    • 1 2 Double Beds
    • Sleeps 4
    • 435 sq ft
  • Suite, Corner

    • 1 1 King Bed
    • Sleeps 3
  • Deluxe Room, 1 King Bed

    • 1 1 King Bed
    • Sleeps 3
    • 350 sq ft

Compare with similar stays

Selected stay

5 Stars

  • Free WiFi
  • Spa
  • Pets
See prices from 10 sites
from$241

Similar stays

  • 4 Stars

    • Free WiFi
    • Pool
    • Spa
    See prices from 18 sites
    from$162
  • 3 Stars

    • Free WiFi
    • Pool
    • Pets
    See prices from 12 sites
    from$195
  • 3 Stars

    • Free WiFi
    • Pool
    • Parking
    See prices from 18 sites
    from$130
  • 3 Stars

    • Pool
    • Parking
    • A/C
    See prices from 1 site
    from$181
  • 3 Stars

    • Free WiFi
    • Pool
    • Parking
    See prices from 13 sites
    from$135
  • 3 Stars

    • Free WiFi
    • Pool
    • Parking
    See prices from 13 sites
    from$168
  • 4 Stars

    • Free WiFi
    • Parking
    • Pets
    See prices from 10 sites
    from$184
  • 3 Stars

    • Free WiFi
    • Parking
    • A/C
    Select dates to see exact prices
  • 3 Stars

    • Pool
    • Parking
    • Pets
    See prices from 12 sites
    from$164
  • 4 Stars

    • Free WiFi
    • Pool
    • Parking
    See prices from 11 sites
    from$144
  • 3 Stars

    • Free WiFi
    • Pool
    • Pets
    See prices from 15 sites
    from$187

Price trend

Based on lowest prices on trivago from the last 30 days
$447
$225
$0

Fri, 06/11/26

N/A

Sat, 07/11/26

$447

Sun, 08/11/26

$265

Mon, 09/11/26

$310

Tue, 10/11/26

N/A

Wed, 11/11/26

$269

Thu, 12/11/26

N/A

Fri, 13/11/26

N/A

Sat, 14/11/26

N/A

Sun, 15/11/26

$265

Mon, 16/11/26

$286

Tue, 17/11/26

N/A

Wed, 18/11/26

$266

Thu, 19/11/26

$266

Fri, 20/11/26

$284

Sat, 21/11/26

$369

Sun, 22/11/26

$266

Mon, 23/11/26

$262

Tue, 24/11/26

$267

Wed, 25/11/26

$281

Thu, 26/11/26

$257

Fri, 27/11/26

N/A

Sat, 28/11/26

N/A

Sun, 29/11/26

N/A

Mon, 30/11/26

N/A

Tue, 01/12/26

N/A

Wed, 02/12/26

N/A

Thu, 03/12/26

N/A

Fri, 04/12/26

$328

Sat, 05/12/26

$355

Sun, 06/12/26

N/A

Mon, 07/12/26

$260

Tue, 08/12/26

N/A

Wed, 09/12/26

$281

Thu, 10/12/26

N/A

Fri, 11/12/26

N/A

Sat, 12/12/26

N/A

Sun, 13/12/26

$257

Mon, 14/12/26

$260

Tue, 15/12/26

N/A

Wed, 16/12/26

N/A

Thu, 17/12/26

N/A

Fri, 18/12/26

$257

Sat, 19/12/26

N/A

Sun, 20/12/26

$260

Mon, 21/12/26

$261

Tue, 22/12/26

N/A

Wed, 23/12/26

$266

Thu, 24/12/26

N/A

Fri, 25/12/26

N/A

Sat, 26/12/26

N/A

Sun, 27/12/26

N/A

Mon, 28/12/26

N/A

Tue, 29/12/26

N/A

Wed, 30/12/26

$353

Thu, 31/12/26

N/A

Fri, 01/01/27

N/A

Sat, 02/01/27

N/A

Sun, 03/01/27

N/A

Reviews

9.2
Excellent
based on 5,783 ratings from top 
sites
sites

Review summary

Summarized by AI from 900+ reviews

This hotel is a vibrant urban hub catering to luxury travelers, sightseers, and groups of friends seeking a unique and immersive experience. Its excellent location in downtown Louisville provides easy walking access to major attractions like the Louisville Slugger Museum, Muhammad Ali Center, and numerous Bourbon distilleries along Whiskey Row. The property distinguishes itself with a unique blend of facilities, notably functioning as an art museum with thought-provoking installations and rotating exhibits. Guests consistently praise the welcoming and professional staff and service, and the on-site restaurant, Proof on Main, is frequently highlighted for its exceptional food and cocktails. For a truly distinctive stay, consider booking the "Asleep in the Cyclone" room, an immersive art installation that doubles as a guest room.

Rated above average for Louisville

Guest reviews

Excellent74%
Very good13%
Good6%
Fair4%
Poor3%

Top amenities

  • WiFi in lobby
  • WiFi in rooms
  • Spa
  • Pets
  • A/C
  • Restaurant
  • Hotel bar
  • Gym

All amenities

Wellness

  1. Beauty salon
  2. Steam room
  3. Massage
  4. Sauna

Property amenities

  1. Business centre
  2. Gym
  3. Porter service
  4. Pet friendly

For children

  1. Cot

Accessibility

  1. Wheelchair accessible
  2. Accessible parking

Room amenities

  1. Shower
  2. Ironing board
  3. Windows that open
  4. Television

Sports facilities

  1. Fitness
  2. Yoga

Hotel theme/type

  1. Convention Centre Hotel
  2. Boutique hotel

Hotel characteristics

  1. Family friendly

Location

700 W Main St, Louisville, 40202, USA

Distance from 21c Museum Hotel Louisville

  1. 0.2 km from Muhammad Ali Center
  2. 0.2 km from Louisville Slugger Museum & Factory
  3. 0.4 km from Louisville (City center)
  4. 0.6 km from Belle of Louisville
  5. 0.7 km from KFC Yum! Center
  6. 1.3 km from Transit Authority of River City
  7. 1.5 km from Louisville Slugger Field
  8. 2.6 km from Lynn Family Stadium
  9. 4.4 km from J B Speed Art Museum
  10. 5.7 km from L&N Federal Credit Union Stadium
  11. 7.6 km from Louisville Zoo
  12. 9.6 km from Louisville Muhammad Ali International Airport

Explore nearby attractions

Property info

700 W Main St, Louisville, 40202, USA

Frequently Asked Questions about 21c Museum Hotel Louisville

  • Is there a pool area at 21c Museum Hotel Louisville?

    No, 21c Museum Hotel Louisville doesn’t offer pool areas.

  • Are pets allowed at 21c Museum Hotel Louisville?

    Yes, 21c Museum Hotel Louisville has a pet policy that may vary based on the room type or availability. Please check with the hotel directly to learn about their pet policy.

  • Is parking available at 21c Museum Hotel Louisville?

    Yes, 21c Museum Hotel Louisville provides Accessible parking for guests.

  • What time is check-in and check-out at 21c Museum Hotel Louisville?

    Check-in at 21c Museum Hotel Louisville is available from: . Check-out time is by .

  • Where is 21c Museum Hotel Louisville located?

    21c Museum Hotel Louisville is located in 700 W Main St, 40202, Louisville, USA.

The prices and availability we receive from booking sites change constantly. This means you may not always find the exact same offer you saw on trivago when you land on the booking site.

Among Top Rated Hotels in Louisville

  • 3 Stars
    Comfort Suites Louisville East
    See prices from 15 sites
    from$107
  • 4 Stars
    Embassy Suites by Hilton Louisville Downtown
    See prices from 12 sites
    from$189
  • 3 Stars
    Quality Inn & Suites University/Airport
    See prices from 15 sites
    from$101
  • 3 Stars
    Hawthorn Suites by Wyndham Louisville East
    See prices from 13 sites
    from$106
  • 4 Stars
    Derby City Gaming & Hotel - A Churchill Downs Property
    Select dates to see exact prices
  • 3 Stars
    Clarion Pointe Louisville East
    Select dates to see exact prices
  • 2 Stars
    HomeTowne Studios Louisville
    Select dates to see exact prices
  • 4 Stars
    Embassy Suites by Hilton Louisville East
    See prices from 13 sites
    from$253
  • 2 Stars
    Comfort Inn Louisville Southwest
    See prices from 15 sites
    from$103

Destinations near 21c Museum Hotel Louisville